Petechiae and a Persistent Violaceous Nodule: A Presentation of Blastic Plasmacytoid Dendritic Cell Neoplasm to Dermatology.

Authors

Madison Anzelc, OhioHealth
Christina Druskovich
Austin Cusick, OhioHealth
Matthew Franklin, OhioHealth

Document Type

Article

Publication Title

Case reports in dermatological medicine

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive CD4+ CD56+ hematopoietic malignancy. The cutaneous presentation is variable but often includes violaceous nodules. We present a rare case of BPDCN, which featured dermatological findings consisting of erythematous macules, petechiae, purpura, and a violaceous nodule. A skin biopsy and peripheral blood smear supported a diagnosis of BPDCN. With BPDCN favoring cutaneous involvement, we urge dermatologists to be aware of the possibility of a BPDCN diagnosis in patients who present with purpuric nodules and petechial skin findings, especially when it is not easily explainable by another pathology or medication.

First Page

8628105

Last Page

8628105

DOI

10.1155/crdm/8628105

Publication Date

1-1-2025

Recommended Citation

Anzelc M, Druskovich C, Cusick A, Franklin M. Petechiae and a Persistent Violaceous Nodule: A Presentation of Blastic Plasmacytoid Dendritic Cell Neoplasm to Dermatology. Case Rep Dermatol Med. 2025 Mar 18;2025:8628105. doi: 10.1155/crdm/8628105. PMID: 40135229; PMCID: PMC11936536.