Achromobacter xylosoxidans: An uncommon scalp infection leading to alopecia and biofilm formation.

Document Type

Article

Publication Title

Diagnostic microbiology and infectious disease

Abstract

Achromobacter xylosoxidans is an emerging opportunistic pathogen causing respiratory and systemic infections, mainly in immunocompromised individuals. Cutaneous infections remain uncommon. We present a unique case of a 60-year-old immunocompetent female with a persistent, pruritic, and malodorous scalp infection for over a year, leading to alopecia and biofilm formation, complicating treatment by increasing antibiotic resistance. Despite lacking typical risk factors, wound culture identified A. xylosoxidans with susceptibility to trimethoprim-sulfamethoxazole, which led to successful treatment alongside surgical debridement. This case highlights the need for clinicians to consider A. xylosoxidans in differential diagnoses of unusual skin infections, especially when biofilm formation is evident, and underscores the importance of targeted antibiotic therapy due to this pathogen's multidrug resistance.

First Page

116797

Last Page

116797

DOI

10.1016/j.diagmicrobio.2025.116797

Publication Date

6-1-2025

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