Document Type
Article
Publication Title
Heart Rhythm O2
Abstract
BACKGROUND: Same-day discharge (SDD) after atrial fibrillation (AF) ablation is generally considered safe, since most complications are identified during (or immediately) after the procedure.
OBJECTIVE: This study aimed to evaluate SDD in the SPHERE Persistent-Atrial Fibrillation trial.
METHODS: Patients with persistent AF were randomized to the dual-energy lattice-tip mapping and ablation catheter (investigational) vs a conventional contact-force radiofrequency ablation system (control). SDD and timing of 30-day procedure- or device-related serious adverse events (SAEs) were assessed in the full cohort. In a subset of centers that performed SDD in the trial, predictors of SDD, 30-day readmissions, and mortality rates were assessed.
RESULTS: SDD was achieved in 229 of 418 (54.8%) patients (55.9% of investigational [n = 211] and 53.6% of control [n = 207;
CONCLUSION: Among the traditional thermal ablation technologies, SDD protocols have been well-established and safely practiced. Here, SDD was safely achieved, with no significant differences in outcome when performed with the investigational system compared with a conventional contact-force radiofrequency ablation system.
First Page
656
Last Page
663
Publication Date
4-1-2026
Recommended Citation
Taigen TL, Nair DG, Sharma D, Kiehl EL, Osorio J, Neuzil P, Kautzner J, Mountantonakis SE, Natale A, Hummel JD, Doshi SK, Amin AK, Siddiqui UR, van Bragt KA, Cerkvenik J, Tarakji KG, Reddy VY, Mansour M, Anter E. Same day discharge can be performed safely after atrial fibrillation catheter ablation using a wide-footprint lattice-tip dual-energy system. Heart Rhythm O2. 2026 Jan 21;7(4):656-663. doi: 10.1016/j.hroo.2026.01.015. PMID: 42038672; PMCID: PMC13107042.