Longitudinal QTc stability and impact of baseline cardiac rhythm on discharge dose in dofetilide-treated patients

Authors

• Zeryab A Khan, OhioHealth
• Megan E LaBreck, OhioHealth
• Jordan Luli, OhioHealth
• Chelsea Roberts, OhioHealth
• Alexander Smith, OhioHealth
• Rayan El-Zein, OhioHealth
• Jaret D Tyler, OhioHealth
• Eugene Y Fu, OhioHealth
• Sreedhar R Billakanty, OhioHealth
• Anish K Amin, OhioHealth
• Nagesh Chopra, OhioHealth

Document Type

Article

Publication Title

Journal of cardiovascular electrophysiology

Abstract

INTRODUCTION: Dofetilide suppresses atrial fibrillation (AF) in a dose-dependent fashion. The protective effect of AF against QT

METHODS: Medical records of patients who underwent preplanned dofetilide loading at a tertiary care center between January 2016 and 2019 were reviewed.

RESULTS: A total of 198 patients (66 ± 10 years, 32% female, CHADS

CONCLUSION: Dofetilide initiation before cardioversion is equivalent to initiation during SR. Significant QT

First Page

1281

Last Page

1289

DOI

10.1111/jce.15483

Publication Date

6-1-2022

Recommended Citation

Khan ZA, LaBreck ME, Luli J, Roberts C, Smith A, El-Zein R, Tyler JD, Fu EY, Billakanty SR, Amin AK, Chopra N. Longitudinal QTc stability and impact of baseline cardiac rhythm on discharge dose in dofetilide-treated patients. J Cardiovasc Electrophysiol. 2022 Jun;33(6):1281-1289. doi: 10.1111/jce.15483. Epub 2022 Apr 17. PMID: 35362175.