Document Type
Article
Publication Title
Front Neurol
Abstract
IMPORTANCE: Stroke-to-recanalization time is a strong predictor of outcomes in anterior circulation large-vessel occlusion (LVO). The authors aimed to evaluate functional outcomes in early (<6 >h) vs. late (6-24 h) time windows for thrombectomy-treated basilar artery occlusions.
METHODS: Patients were derived from the Posterior Circulation Ischemic Stroke Evaluation: Analyzing Radiographic and Intra-procedural Predictors of Mechanical Thrombectomy (PC-SEARCH) Registry and retrospectively analyzed early and late basilar artery thrombectomy time windows cohorts. Patients were dichotomized based on the last known well and correlated to 90-day functional outcomes (mRS 0-3). A multiple logistic regression analysis was performed.
RESULTS: A total of 405 patients were included in this study: 216 and 189 patients in the early and late time windows, respectively. Baseline demographic, stroke, radiographic, and intraprocedural characteristics were similar between the groups. A total of 99 (46%) and 79 (42%) patients in the early and late time windows, respectively, achieved favorable functional outcomes at 90 days (
CONCLUSION: The early and late thrombectomy time windows can achieve similar rates of 90-day favorable functional outcomes. However, timely thrombectomy influences the likelihood of achieving excellent functional outcomes (mRS ≤ 2) within the early time window.
First Page
1352310
Last Page
1352310
DOI
10.3389/fneur.2024.1352310
Publication Date
1-1-2024
Recommended Citation
Mierzwa, Adam T; Rao, Rahul; Al Kasab, Sami; Nelson, Ashley; Ortega-Gutierrez, Santiago; Vivanco-Suarez, Juan; Farooqui, Mudassir; Jadhav, Ashutosh P; Desai, Shashvat; Toth, Gabor; Alrohimi, Anas; Nguyen, Thanh N; Klein, Piers; Abdalkader, Mohamad; Salahuddin, Hisham; Pandey, Aditya; Wilseck, Zachary; Koduri, Sravanthi; Vora, Nirav; Aladamat, Nameer; Gharaibeh, Khaled; Afreen, Ehad; Zaidi, Syed; and Jumaa, Mouhammad, "Early and Late Basilar Artery Thrombectomy Time Window Outcomes." (2024). Neuroscience Articles. 20.
https://scholarlyworks.ohiohealth.com/neuroscience-articles/20