Clinical Profile and Outcomes of COVID-19-Associated Transverse Myelitis: A Case Report and Review of Literature.

Document Type

Article

Publication Title

Neurology. Clinical practice

Abstract

PURPOSE OF REVIEW: The purpose of this study was to evaluate demographics, clinical profiles, and outcomes of transverse myelitis (TM) in the setting of COVID-19 infection (iTM) or vaccination (vTM) and to describe a case of spontaneous resolution of iTM.

RECENT FINDINGS: Of a total of 158 articles that met our search criteria, 30 articles detailing 65 unique cases were included, of which 48 (73.8%) were iTM and 17 (26.2%) were vTM. The mean age of the iTM group was significantly lower as compared with vTM (43 ± 20.3 years vs 56.4 ± 18.6 years;

SUMMARY: There are no significant differences with respect to time to presentation, clinical and radiological features, and in outcomes between iTM and vTM, suggesting a common pathogenesis. Approximately 80% of cases have a good outcome. Hence, early recognition and treatment are important. Our case demonstrates that treatment should be based on the clinical presentation rather than laboratory or imaging features.

First Page

221

Last Page

221

DOI

10.1212/CPJ.0000000000200094

Publication Date

12-1-2022

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