Document Type
Article
Publication Title
Case reports in hematology
Abstract
Myeloproliferative disorders are variable disorders, based on the genetic abnormality present and the cell line progenitors that are affected. In this case, we discuss a novel gene translocation in the subset of PDGFRB mutations, first seen with prominent hyperbasophilia. This case demonstrates the possibility for lower therapeutic doses of imatinib mesylate than previously reported, in order to control leukocyte counts and reverse the genetic mutation.
First Page
709164
Last Page
709164
DOI
10.1155/2013/709164
Publication Date
1-1-2013
Recommended Citation
Provenzano JD, Kuebler JP. Novel t(5;19) Translocation in a Patient with PDGFRB Associated Chronic Leukemia: Implications for Treatment Strategy. Case Rep Hematol. 2013;2013:709164. doi: 10.1155/2013/709164. Epub 2013 Jul 10. PMID: 23936692; PMCID: PMC3722963.