Transcatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk.
Document Type
Article
Publication Title
The American journal of cardiology
Abstract
There are limited data from randomized controlled trials assessing the impact of transcatheter aortic valve replacement (TAVR) or surgery in women with aortic stenosis and small aortic annuli. We evaluated 2-year clinical and hemodynamic outcomes after aortic valve replacement to understand acute valve performance and early and midterm clinical outcomes. This post hoc analysis pooled women enrolled in the randomized, prospective, multicenter Evolut Low Risk and Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI) intermediate risk trials. Women with severe aortic stenosis at low or intermediate surgical risk who had a computed tomography-measured annular perimeter of ≤72.3 mm were included and underwent self-expanding, supra-annular TAVR or surgery. The primary end point was 2-year all-cause mortality or disabling stroke rate. The study included 620 women (323 TAVR, 297 surgery) with a mean age of 78 years. At 2 years, the all-cause mortality or disabling stroke was 6.5% for TAVR and 8.0% for surgery, p = 0.47. Pacemaker rates were 20.0% for TAVR and 8.3% for surgery, p
First Page
147
Last Page
155
DOI
10.1016/j.amjcard.2024.04.013
Publication Date
7-15-2024
Recommended Citation
Modine, Thomas; Forrest, John K; Van Mieghem, Nicolas M; Deeb, G Michael; Yakubov, Steven J; Ali, Walid Ben; Tchétché, Didier; Lam, Ka Yan; Oh, Jae K; Huang, Jian; Mehran, Roxana; and Reardon, Michael J, "Transcatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk." (2024). Heart and Vascular Articles. 34.
https://scholarlyworks.ohiohealth.com/heart-vascular-articles/34

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